Genetic diversity has long been acknowledged as an important management consideration in conservation translocations. Initially, conservation programs aimed to capture 90-95% of the diversity of source populations. As the field of translocation has matured and the practice has become largely routine, more sophisticated genetic objectives have been developed, such as an effective population size (Ne) >500/1000 and metapopulation management. In parallel, a paradigm shift has occurred from prioritizing locally sourced founders towards maximizing diversity through multi-source founding populations as the risk of outbreeding is generally low and the risks of inbreeding and low adaptive potential are much higher. However, many reintroduced populations may never reach a large enough Ne to prevent drift and re-establishing natural connectivity to conspecific populations is not always possible. This raises the questions of how much diversity is enough and when is genetic management needed in translocated populations. Here, we describe a framework of genetic metrics and targets that can be applied to metapopulation management for threatened species being restored through translocations. The framework outlines conceptual targets for single populations in a metapopulation network, including the metrics and thresholds that apply for monitoring success in single translocations and triggering actions such as genetic supplementation. Additionally, conceptual targets and metrics to evaluate the genetic health of the metapopulation will be detailed, drawing on several Australian mammal examples. As conservation translocations become more common, strategic metapopulation management is becoming central to successfully recovering species and effectively conserving their remnant genetic diversity.